Condensed Tannins Improve Glycolipid Metabolism but Induce Liver Injury of Chinese Seabass (Lateolabrax maculatus)

A 63-day feeding trial with 640 juvenile L. maculatus was conducted to assess the effects of dietary CT on serum metabolites, antioxidant and immune response, liver histomorphology glycometabolism enzyme activities fish. Four diets were formulated contain 0 (T1), 1 (T2), 2 (T3), g/kg plus 4 polyethylene glycol (PEG) (T4). PEG specifically binds neutralize activity. Fish randomly distributed into 16 tanks (4 per group 40 fish tank) fed apparent satiation twice daily. Results indicated that T2 T3 had lower ( P <0.05) concentrations albumin, total cholesterol triacylglycerol, but higher alanine aminotransferase activity than T1 T4. glucose insulin other groups. superoxide dismutase, catalase, lysozyme globulin M Compared T4, hepatocytes in shown have obvious vacuolar degeneration along different degree inflammatory cell infiltration. values eosinophilic infiltrate necrosis greater pyruvate kinase, glucokinase those All parameters similar >0.05) between In summary, up reduced lipid concentrations, enhanced improved utilization . induced injury which provided a caution for its application aquaculture.